Ndi zodzoladzola zachilengedwe, zobiriwira, zathanzi komanso zotetezeka zokhala ndi zotsalira za zomera zomwe zimakopa chidwi chochulukirapo, chitukuko cha zinthu zogwira ntchito kuchokera ku zomera ndi chitukuko cha zodzoladzola zachilengedwe zakhala imodzi mwamitu yogwira ntchito kwambiri pa chitukuko cha zodzoladzola. Kukonzanso zopangira zomera sikungobwezeretsa mbiri yakale, koma kusunga chikhalidwe cha chikhalidwe cha Chitchaina, kugwirizanitsa ziphunzitso zachikhalidwe za chikhalidwe cha China, ndikugwiritsa ntchito teknoloji yamakono ya biochemical kupanga mitundu yatsopano ya zodzoladzola zochokera ku zomera, kuti pakhale chitukuko cha sayansi ndi chitetezo. zodzoladzola zachilengedwe. Mankhwala opangira mankhwala amapereka zobiriwira zobiriwira. Kuphatikiza apo, zowonjezera zamasamba zimagwiritsidwa ntchito kwambiri muzamankhwala, zowonjezera zakudya, zakudya zogwira ntchito, zakumwa, zodzoladzola ndi zina.
Zomera Zomera(PE) imatanthawuza zomera zomwe zimakhala ndi mamolekyu ang'onoang'ono achilengedwe ndi ma macromolecules monga thupi lalikulu lopangidwa ndi cholinga cholekanitsa ndi kuyeretsa chinthu chimodzi kapena zingapo zomwe zimagwira ntchito muzopangira zomera pogwiritsa ntchito njira zakuthupi, zamankhwala ndi zachilengedwe. Zodzoladzola zopangidwa ndi zopangira zopangira zogwira ntchito zimakhala ndi ubwino wambiri poyerekeza ndi zodzoladzola zachikhalidwe: zimagonjetsa zofooka za zodzoladzola zachikhalidwe zomwe zimadalira mankhwala opangira mankhwala, zomwe zimapangitsa kuti mankhwalawa akhale otetezeka; zigawo zachilengedwe zimatengedwa mosavuta ndi khungu, zomwe zimapangitsa kuti mankhwalawa akhale othandiza komanso zotsatira zake zimakhala zofunikira kwambiri; ntchitoyo ndi yotchuka kwambiri, etc.
Kusankha chotsitsa choyenera cha chomera ndikuwonjezera kuchuluka kwamitengo yamafuta kuzinthu zodzikongoletsera kumatha kukulitsa zotsatira zake. Ntchito zazikuluzikulu zopangira zodzoladzola zodzikongoletsera ndi: kunyowa, kuletsa kukalamba, kuchotsa madontho, kuteteza dzuwa, antiseptic, etc., ndi zotulutsa zomera ndizobiriwira komanso zotetezeka.
Moisturizing zotsatira
The moisturizing katundu mu zodzoladzola makamaka ikuchitika m'njira ziwiri: mmodzi zimatheka ndi madzi-kutsekera zotsatira kupanga hydrogen zomangira moisturizing wothandizila ndi madzi mamolekyu; china ndi chakuti mafuta amapanga filimu yotsekedwa pakhungu.
Zodzoladzola zotchedwa moisturizing zodzoladzola ndi zodzoladzola zomwe zimakhala ndi zowonjezera zowonongeka kuti zikhalebe ndi chinyezi cha stratum corneum kuti zibwezeretse kukongola ndi kusungunuka kwa khungu. Zodzoladzola zowonongeka zimagawidwa m'magulu awiri malinga ndi makhalidwe awo: imodzi ndiyo kugwiritsa ntchito zinthu zosungira madzi zomwe zingathe kuphatikizidwa mwamphamvu ndi chinyezi pamwamba pa khungu kuti zinyowetse stratum corneum, yotchedwa moisturizing agents, monga glycerin; chinacho ndi chinthu chomwe sichisungunuka m'madzi, filimu yopaka mafuta imapangidwa pamwamba pa khungu, yomwe imakhala ngati chisindikizo kuti madzi asatayike, kotero kuti stratum corneum imakhala ndi chinyezi, chotchedwa emollients kapena zoziziritsa kukhosi, monga petrolatum, mafuta, ndi sera.
Pali zomera zingapo muzomera zomwe zimakhala ndi hydrating ndi moisturizing, monga aloe vera, udzu wam'nyanja, azitona, chamomile, ndi zina zotero, zonse zimakhala ndi mphamvu zowonongeka.
Anti-kukalamba zotsatira
Ndi kukula kwa ukalamba, khungu limayamba kusonyeza ukalamba boma, amene makamaka kuchepetsa kolajeni, elastin, mucopolysaccharide ndi zina zili pakhungu ndi madigiri osiyanasiyana, Mitsempha kupereka khungu zakudya atrophy, elasticity wa chotengera cha magazi. khoma amachepetsa, ndi khungu epidermis pang`onopang`ono thins. Kutupa, subcutaneous mafuta kuchepetsa, ndi maonekedwe a makwinya, chloasma ndi zaka mawanga.
Pakadali pano, kafukufuku wam'mbuyomu wokhudza zomwe zimayambitsa ukalamba wa anthu afotokoza mwachidule zinthu izi:
Chimodzi ndi kuwonjezeka ndi kukalamba kwa ma free radicals. Ma radicals aulere ndi ma atomu kapena mamolekyu okhala ndi ma elekitironi osalumikizana omwe amapangidwa ndi homolysis ya covalent bond. Iwo ali ndi mlingo wapamwamba wa mankhwala ndipo adutsa peroxidation ndi unsaturated lipids. Lipid peroxide (LPO), ndi mankhwala ake omaliza, malondialdehyde (MDA), amatha kuchitapo kanthu ndi zinthu zambiri m'maselo amoyo, zomwe zimapangitsa kuchepa kwa biofilm permeability, kuwonongeka kwa mamolekyu a DNA, ndi kufa kwa selo kapena kusintha.
Chachiwiri, kuwala kwa UVB ndi UVA padzuwa kumatha kuyambitsa khungu. Ma radiation a Ultraviolet makamaka amayambitsa kukalamba kwa khungu kudzera m'njira zotsatirazi: 1) kuwonongeka kwa DNA; 2) kugwirizanitsa kwa collagen; 3) kuchepetsa kuyankhidwa kwa chitetezo cha mthupi mwa kuyambitsa njira yoletsa kuyankha kwa antigen-stimulated; 4) m'badwo wa zotakasika kwambiri free ankafuna kusintha zinthu mopitirira kucheza ndi osiyanasiyana okhudza maselo ambiri nyumba 5. Mwachindunji ziletsa ntchito epidermal Langerhans maselo, kuchititsa photoimmunosuppression ndi kufooketsa chitetezo cha m'thupi ntchito pakhungu. Kuphatikiza apo, glycosylation yopanda enzymatic, zovuta za metabolic, ndi ukalamba wa matrix metalloproteinase zidzakhudzanso ukalamba wa khungu.
Zomera zamasamba monga zoletsa zachilengedwe za elastase zakhala nkhani yotentha kwambiri m'zaka zaposachedwa, monga Scutellaria baikalensis, Burnet, Morinda citrifolia mbewu, Moringa, Shuihe, Forsythia, Salvia, Angelica ndi zina zotero. Zotsatira za kafukufukuyu zikuwonetsa kuti: Salvia miltiorrhiza extract (ESM) imatha kulimbikitsa mafotokozedwe a filaggrin mu ma keratinocyte wamba amunthu ndi khungu la AmoRe, lomwe limatha kupititsa patsogolo ntchito ya kusiyanitsa kwa epidermal ndi hydration, ndikuthandizira kukana kukalamba ndi kunyowa. ; kuchokera ku zomera zodyedwa Chotsani anti-free radical DPPH yogwira mtima, ndikuyiyika kuzinthu zodzikongoletsera zoyenera, ndi zotsatira zabwino; Kutulutsa kwa polygonum cuspidatum kumakhala ndi zoletsa zina pa elastase, potero odana ndi ukalamba komanso odana ndi makwinya.
Fsasamala
Kusiyana kwa khungu la thupi la munthu nthawi zambiri kumadalira zomwe zili ndi kugawa kwa epidermal melanin, kufalikira kwa magazi a dermis, ndi makulidwe a stratum corneum. Kudetsedwa kwa khungu kapena kupangika kwa mawanga akuda kumakhudzidwa makamaka ndi kudzikundikira kwa melanin wambiri, okosijeni wa khungu, keratinocyte deposition, khungu losayenda bwino la microcirculation, komanso kudzikundikira kwa poizoni m'thupi.
Masiku ano, zotsatira za kuchotsa freckle zimatheka makamaka pokhudza mapangidwe ndi kuchuluka kwa melanin. Imodzi ndi tyrosinase inhibitor. Pakutembenuka kuchokera ku tyrosine kupita ku dopa ndi dopa kupita ku dopaquinone, onsewa amathandizidwa ndi tyrosinase, yomwe imayang'anira mwachindunji kuyambika ndi liwiro la kaphatikizidwe ka melanin, ndikuzindikira ngati njira zotsatila zitha kupitilira.
Pamene zinthu zosiyanasiyana zochita pa tyrosinase kuonjezera ntchito yake, melanin kaphatikizidwe ukuwonjezeka, ndipo pamene ntchito tyrosinase oletsedwa, melanin synthesis amachepetsa. Kafukufuku wasonyeza kuti arbutin amatha kuletsa ntchito ya tyrosinase m'gulu la ndende popanda poizoni wa melanocyte, kulepheretsa kaphatikizidwe ka dopa, motero kuletsa kupanga melanin. Ofufuza adaphunzira zamagulu amtundu wa tiger wakuda ndi zoyera zake, ndikuwunika kupsa mtima kwapakhungu.
Zotsatira zafukufuku zimasonyeza kuti: pakati pa 17 yokhayokha (HLH-1～17), HLH-3 ikhoza kulepheretsa mapangidwe a melanin, kuti akwaniritse zotsatira za kuyera, ndipo chotsitsacho chimakhala ndi mkwiyo wochepa kwambiri pakhungu. Ren Hongrong et al. atsimikizira kudzera muzoyesa kuti mafuta onunkhira a lotus mowa amalepheretsa kupanga melanin. Monga mtundu watsopano wa zoyera zomwe zimachokera ku zomera, zimatha kusakanikirana ndi zonona zoyenera ndipo zimatha kupangidwa kukhala chisamaliro cha khungu, anti-kukalamba ndi kuchotsa ma freckle. Zodzoladzola Zogwira Ntchito.
Palinso melanocyte cytotoxic wothandizira, monga endothelin antagonists opezeka zomera akupanga, amene akhoza mpikisano ziletsa kumanga endothelin kuti melanocyte nembanemba zolandilira, ziletsa kusiyanitsa ndi kuchuluka kwa melanocytes, kuti ziletsa ndi ultraviolet poizoniyu induces cholinga cha melanin. kupanga. Kudzera mu kuyesa kwa ma cell, Frédéric Bonté et al. adawonetsa kuti ma orchid atsopano a Brassocattleya amatha kuletsa kufalikira kwa ma melanocyte. Kuwonjezera pa zodzoladzola zoyenera kumapangitsa kuti khungu likhale loyera komanso lowala. Zhang Mu et al. yotengedwa ndi kuphunzira Chinese zitsamba akupanga monga Scutellaria baicalensis, Polygonum cuspidatum ndi Burnet, ndipo zotsatira anasonyeza kuti akupanga akhoza ziletsa selo kuchulukana mosiyanasiyana, ziletsa kwambiri ntchito ya okhudza maselo ambiri tyrosinase, ndi kuchepetsa kwambiri okhudza maselo ambiri melanin okhutira, kuti akwaniritse zotsatira za freckle whitening.
chitetezo cha dzuwa
Nthawi zambiri, mafuta oteteza ku dzuwa omwe amagwiritsidwa ntchito kwambiri pa zodzoladzola zodzitetezera ku dzuwa amagawidwa m'magulu awiri: imodzi ndi UV absorbers, yomwe ndi mankhwala achilengedwe, monga ketoni; ina ndi UV shielding agents, ndiko kuti, zoteteza dzuwa, monga TiO2, ZnO. Koma mitundu iwiriyi ya mafuta oteteza ku dzuwa imatha kuyambitsa kupsa mtima kwapakhungu, kuyabwa pakhungu, ndi kutsekeka kwa pores. Komabe, zomera zambiri zachilengedwe zimakhala ndi mayamwidwe abwino pa cheza cha ultraviolet, ndipo mosalunjika zimalimbitsa ntchito zoteteza dzuwa pochepetsa kuwonongeka kwa cheza cha ultraviolet pakhungu.
Kuphatikiza apo, zopangira zodzitetezera ku dzuwa zomwe zili muzomera zimakhala ndi zabwino zochepetsera kupsa mtima kwapakhungu, kukhazikika kwazithunzi, chitetezo ndi kudalirika poyerekeza ndi mankhwala azikhalidwe komanso zoteteza dzuwa. Zheng Hongyan et al. adasankha zopangira zitatu zachilengedwe, cortex, resveratrol ndi arbutin, ndipo adaphunzira zachitetezo ndi UVB ndi UVA zodzitchinjiriza zodzoladzola zawo zoteteza dzuwa kudzera m'mayesero amunthu. Zotsatira za kafukufuku zikuwonetsa kuti: zotulutsa zina zachilengedwe zimawonetsa chitetezo chabwino cha UV. Direction ndi ena adagwiritsa ntchito tartary buckwheat flavonoids ngati zida zopangira kuti aphunzire mawonekedwe a dzuwa a flavonoids. Kafukufukuyu adapeza kuti kugwiritsa ntchito ma flavonoids ku emulsions yeniyeni ndikuphatikiza ndi zoteteza thupi ndi mankhwala zoteteza dzuwa kumapereka maziko ofotokozera akugwiritsa ntchito zodzikongoletsera zamaluwa muzodzola mtsogolo.
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Nthawi yotumiza: Jul-12-2022