Anthu ambiri amadziwa za Parkinson's ndi Alzheimer's. Matenda a Parkinson ndi matenda wamba a neurodegenerative. Ndilofala kwambiri mwa okalamba. Avereji ya zaka zoyambira ndi pafupifupi zaka 60. Achinyamata omwe amayamba ndi matenda a Parkinson osakwana zaka 40 ndi osowa. Kukula kwa PD pakati pa anthu opitilira zaka 65 ku China kuli pafupifupi 1.7%. Odwala ambiri omwe ali ndi matenda a Parkinson amangochitika mwapang'onopang'ono, ndipo odwala ochepera 10% amakhala ndi mbiri yabanja. Kusintha kwakukulu kwa pathological mu matenda a Parkinson ndiko kuwonongeka ndi kufa kwa dopaminergic neurons mu substantia nigra ya midbrain. Chifukwa chenicheni cha kusintha kwa pathological ichi sichikudziwikabe. Ma genetic, zinthu zachilengedwe, ukalamba, komanso kupsinjika kwa okosijeni zonse zitha kukhudzidwa pakuwonongeka ndi kufa kwa PH dopaminergic neurons. Mawonetseredwe ake azachipatala makamaka akuphatikizapo kupumula kunjenjemera, bradykinesia, myotonia ndi postural gait chisokonezo, pamene odwala akhoza kutsagana ndi zizindikiro zosayendetsa galimoto monga kuvutika maganizo, kudzimbidwa ndi kusokonezeka kwa tulo.
Dementia, yomwe imadziwikanso kuti Alzheimer's disease, ndi matenda omwe amayamba pang'onopang'ono ndipo amayamba mobisa. Kachipatala, amadziwika ndi kusokonezeka kwa kukumbukira, aphasia, apraxia, agnosia, kuwonongeka kwa luso la visuospatial, kulephera kugwira ntchito bwino, komanso kusintha kwa umunthu ndi khalidwe. Omwe amayamba asanafike zaka 65 amatchedwa matenda a Alzheimer's; omwe amayamba zaka 65 atakwanitsa zaka 65 amatchedwa Alzheimer's.
Matenda awiriwa nthawi zambiri amavutitsa okalamba ndipo amachititsa ana kukhala ndi nkhawa. Choncho, momwe mungapewere kuchitika kwa matenda awiriwa nthawi zonse akhala akufufuza kafukufuku wa akatswiri. China ndi dziko lalikulu lopanga tiyi ndi kumwa tiyi. Kuwonjezera pa kuchotsa mafuta ndi kuchotsa mafuta, tiyi ali ndi phindu losayembekezereka, ndiko kuti, akhoza kuteteza matenda a Parkinson ndi Alzheimer's.
Tiyi wobiriwira ali ndi chinthu chofunikira kwambiri chogwira ntchito: epigallocatechin gallate, yomwe ndi yothandiza kwambiri mu tiyi polyphenols ndipo ndi ya makatekini.
Kafukufuku wambiri wasonyeza kuti epigallocatechin gallate imateteza mitsempha kuti isawonongeke mu matenda a neurodegenerative. Kafukufuku wamakono a epidemiological awonetsa kuti kumwa tiyi kumayenderana moyipa ndi kupezeka kwa matenda ena a neurodegenerative, kotero akuti kumwa tiyi kumatha kuyambitsa njira zodzitetezera m'maselo a neuronal. EGCG imakhalanso ndi antidepressant effect, ndipo ntchito yake yodetsa nkhawa imakhala yogwirizana kwambiri ndi kuyanjana kwa γ-aminobutyric acid receptors. Kwa anthu omwe ali ndi kachilombo ka HIV, neurodementia yoyambitsidwa ndi kachilomboka ndi njira yoyambitsa matenda, ndipo kafukufuku waposachedwapa wasonyeza kuti EGCG ikhoza kuletsa izi.
EGCG imapezeka makamaka mu tiyi wobiriwira, koma osati mu tiyi wakuda, kotero kapu ya tiyi yoyera mutatha kudya imatha kuchotsa mafuta ndikuchotsa mafuta, omwe ndi athanzi kwambiri. EGCE yotengedwa ku tiyi wobiriwira ingagwiritsidwe ntchito pazinthu zathanzi ndi zakudya zowonjezera zakudya, ndipo ndi chida chachikulu chotetezera matenda omwe tawatchulawa.
Nthawi yotumiza: Apr-06-2022